Target

Gene symbol :  
Sorl1
NCBI gene ID :  
20660
Gene full name :  
Sortilin related receptor 1
Synonym :  
LR11, SorLA

Protein function

Protein name :  
Sortilin-related receptor
Endocytic receptor involved in protein trafficking and amyloid precursor protein processing

Expected phenotype

Altered neuronal trafficking and amyloid processing

Human disease relevance

Alzheimer disease

Model applications

Neurodegeneration and trafficking models

Keywords:

receptor, endocytosis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sorl1

conditional Knockout mouse

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