Target

Gene symbol :  
Sparc
NCBI gene ID :  
20692
Gene full name :  
Secreted protein acidic and rich in cysteine
Synonym :  
Osteonectin, BM-40

Protein function

Protein name :  
SPARC
Matricellular protein involved in cell–matrix interactions and tissue remodeling

Expected phenotype

Growth abnormalities, impaired wound healing

Human disease relevance

Altered tumor stroma, fibrotic diseases

Model applications

ECM biology, fibrosis, tumor microenvironment

Keywords:

ECM, Tissue remodeling, Fibrosis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sparc

conditional Knockout mouse

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