Sptbn2 conditional Knockout mouse

Target

Gene symbol :

Sptbn2

NCBI gene ID :

20743

Gene full name :

Spectrin beta chain, non-erythrocytic 2

Synonym :

Beta-III spectrin, SCA5, ALS5

Protein function

Protein name :

SPTBN2

Structural support in dendrites; scaffolding for receptor complexes

Expected phenotype

Ataxia-like gait, Purkinje cell degeneration

Human disease relevance

Mutations cause spinocerebellar ataxia type 5

Model applications

Neurodegeneration, motor coordination studies

Keywords:

Spectrin, Ataxia, Neurodegeneration

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Sptbn2

conditional Knockout mouse

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