Stambp conditional Knockout mouse

Target

Gene symbol :

Stambp

NCBI gene ID :

70527

Gene full name :

STAM binding protein

Synonym :

AMSH, MpnD

Protein function

Protein name :

STAM-binding protein

Deubiquitinating enzyme; regulates endosomal sorting via ESCRT pathway

Expected phenotype

Knockouts show neurodegeneration and growth retardation

Human disease relevance

Mutations cause microcephaly-capillary malformation syndrome

Model applications

Studied in neurodegeneration, ubiquitin signaling, and endocytosis

Keywords:

Deubiquitination, ESCRT, Neurodegeneration, Ubiquitin

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Stambp

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe