Stat1 conditional Knockout mouse

Target

Gene symbol :

Stat1

NCBI gene ID :

20846

Gene full name :

Signal transducer and activator of transcription 1

Synonym :

Signal transducer and activator of transcription 1, ISGF3G

Protein function

Protein name :

STAT1 transcription factor

Mediates interferon signaling and immune response through transcriptional activation

Expected phenotype

Severe defects in antiviral immunity and interferon response

Human disease relevance

Immunodeficiency, autoimmune disease

Model applications

Innate immunity and cytokine signaling models

Keywords:

interferon signaling, transcription

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Stat1

conditional Knockout mouse

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