Target

Gene symbol :  
Synj1
NCBI gene ID :  
104015
Gene full name :  
Synaptojanin 1
Synonym :  
Synaptojanin 1

Protein function

Protein name :  
Synaptojanin-1
Phosphoinositide phosphatase involved in synaptic vesicle recycling

Expected phenotype

Knockouts show synaptic transmission defects and seizures

Human disease relevance

Mutations cause Parkinson’s disease and epilepsy

Model applications

Used in neurodegeneration and synaptic plasticity models

Keywords:

Synapse, Endocytosis, Phosphatase, Parkinson’s disease

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Synj1

conditional Knockout mouse

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