Target

Gene symbol :  
Tacr1
NCBI gene ID :  
21336
Gene full name :  
Tachykinin receptor 1
Synonym :  
NK1R

Protein function

Protein name :  
Neurokinin-1 receptor
G protein-coupled receptor for substance P, mediates pain signaling and inflammation

Expected phenotype

Altered nociception and inflammatory responses

Human disease relevance

Pain disorders, psychiatric diseases

Model applications

Pain signaling and neuropharmacology models

Keywords:

GPCR, neuropeptide signaling

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Tacr1

conditional Knockout mouse

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