Tbc1d2b conditional Knockout mouse

Target

Gene symbol :

Tbc1d2b

NCBI gene ID :

67016

Gene full name :

TBC1 domain–family member 2B

Synonym :

Armus, TBC1-domain family member 2B

Protein function

Protein name :

TBC1D2B

Rab GAP specific for Rab7; regulates endosome–lysosome traffic

Expected phenotype

Endosomal trafficking defects

Human disease relevance

May relate to neurodegeneration and lysosomal disorders

Model applications

Vesicle trafficking and neurobiology models

Keywords:

Rab GAP, Trafficking, Endosome

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Tbc1d2b

conditional Knockout mouse

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