Tbl1xr1 conditional Knockout mouse

Target

Gene symbol :

Tbl1xr1

NCBI gene ID :

81004

Gene full name :

Transducin (beta)-like 1X‑linked receptor 1

Synonym :

8030499H02Rik, A630076E03Rik, C21, DC42, Ira1, TBLR1

Protein function

Protein name :

TBL1XR1

Corepressor/coactivator in N-CoR/HDAC3 complex; regulates transcription and metabolism

Expected phenotype

Knockouts affect transcriptional regulation and metabolic development

Human disease relevance

Mutations cause Pierpont syndrome and cancer associations

Model applications

Studied in chromatin regulation, nuclear receptor biology, and cancer

Keywords:

Transcription regulation, HDAC complex, Nuclear receptor, Metabolism

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Tbl1xr1

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe