Target

Gene symbol :  
Tcf7
NCBI gene ID :  
21414
Gene full name :  
Transcription factor 7
Synonym :  
Tcf-1, TCF1

Protein function

Protein name :  
TCF7 transcription factor
HMG-box transcription factor mediating Wnt signaling and T cell development

Expected phenotype

Defective T cell differentiation and immune function

Human disease relevance

Immunodeficiency, cancer

Model applications

Immunology and Wnt signaling models

Keywords:

Wnt signaling, T cell development

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Tcf7

conditional Knockout mouse

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