Target

Gene symbol :  
Thg1l
NCBI gene ID :  
66628
Gene full name :  
tRNA-histidine guanylyltransferase-like protein
Synonym :  
tRNA-histidine guanylyltransferase-like protein

Protein function

Protein name :  
THG1L
Adds guanosine to 5′ end of tRNA-histidine; key to tRNA functionality

Expected phenotype

tRNA maturation/developmental issues

Human disease relevance

Impacts translation accuracy; under investigation in genetic disorders

Model applications

tRNA processing and translation models

Keywords:

tRNA, Translation, RNA modification

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Thg1l

conditional Knockout mouse

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