Target

Gene symbol :  
Thra
NCBI gene ID :  
21833
Gene full name :  
Thyroid hormone receptor alpha
Synonym :  
c-ErbAalpha, NR1A1

Protein function

Protein name :  
Thyroid hormone receptor alpha
Nuclear receptor mediating thyroid hormone signaling and regulating metabolism and development

Expected phenotype

Altered metabolism, growth defects, and developmental abnormalities

Human disease relevance

Thyroid hormone resistance, metabolic disorders

Model applications

Endocrinology and metabolism models

Keywords:

nuclear receptor, thyroid hormone

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Thra

conditional Knockout mouse

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