Tiam1 conditional Knockout mouse

Target

Gene symbol :

Tiam1

NCBI gene ID :

21844

Gene full name :

T cell lymphoma invasion and metastasis 1

Synonym :

STEF

Protein function

Protein name :

Tiam1 guanine nucleotide exchange factor

Activates Rac1 GTPase, regulating cytoskeleton dynamics and cell migration

Expected phenotype

Impaired cell migration and neuronal development

Human disease relevance

Cancer metastasis

Model applications

Cytoskeleton and signaling models

Keywords:

Rac signaling, cell migration

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Tiam1

conditional Knockout mouse

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