Timmdc1 conditional Knockout mouse

Target

Gene symbol :

Timmdc1

NCBI gene ID :

76916

Gene full name :

Translocase of inner mitochondrial membrane domain containing 1

Synonym :

—

Protein function

Protein name :

TIMMDC1

Component of mitochondrial complex I assembly machinery

Expected phenotype

Knockouts disrupt complex I function and mitochondrial respiration

Human disease relevance

Mutations cause mitochondrial complex I deficiency

Model applications

Studied in mitochondrial biogenesis and metabolic disease

Keywords:

Mitochondria, Complex I, TIM complex, Oxidative phosphorylation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Timmdc1

conditional Knockout mouse

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