Target

Gene symbol :  
Timmdc1
NCBI gene ID :  
76916
Gene full name :  
Translocase of inner mitochondrial membrane domain containing 1
Synonym :  

Protein function

Protein name :  
TIMMDC1
Component of mitochondrial complex I assembly machinery

Expected phenotype

Knockouts disrupt complex I function and mitochondrial respiration

Human disease relevance

Mutations cause mitochondrial complex I deficiency

Model applications

Studied in mitochondrial biogenesis and metabolic disease

Keywords:

Mitochondria, Complex I, TIM complex, Oxidative phosphorylation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Timmdc1

conditional Knockout mouse

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