Tln1 conditional Knockout mouse

Target

Gene symbol :

Tln1

NCBI gene ID :

21894

Gene full name :

Talin 1

Synonym :

Talin, TLN

Protein function

Protein name :

Talin-1

Cytoskeletal protein linking integrins to actin, regulating cell adhesion and signaling

Expected phenotype

Embryonic lethality, impaired cell adhesion and migration

Human disease relevance

Cancer, cardiovascular disease

Model applications

Cell adhesion and mechanotransduction models

Keywords:

integrin signaling, cytoskeleton

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Tln1

conditional Knockout mouse

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