Target

Gene symbol :  
Tmem18
NCBI gene ID :  
211986
Gene full name :  
Transmembrane protein 18
Synonym :  

Protein function

Protein name :  
Transmembrane protein 18
Nuclear envelope protein involved in neuronal differentiation and energy regulation

Expected phenotype

Knockouts show altered energy homeostasis and increased food intake

Human disease relevance

Associated with obesity and BMI in genome-wide studies

Model applications

Studied in obesity, energy balance, and neurodevelopment

Keywords:

Obesity, Energy metabolism, Transmembrane, Hypothalamus

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Tmem18

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe