Target

Gene symbol :  
Tmprss6
NCBI gene ID :  
71753
Gene full name :  
Transmembrane serine protease 6
Synonym :  
Matriptase-2

Protein function

Protein name :  
Matriptase-2
Regulates iron homeostasis via hepcidin pathway

Expected phenotype

Iron deficiency anemia phenotype

Human disease relevance

Iron-refractory iron deficiency anemia

Model applications

Iron metabolism and hematology models

Keywords:

iron regulation, protease

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Tmprss6

conditional Knockout mouse

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