Tnfrsf1a conditional Knockout mouse

Target

Gene symbol :

Tnfrsf1a

NCBI gene ID :

21937

Gene full name :

Tumor necrosis factor receptor superfamily 1A

Synonym :

TNFR1, p55, CD120a

Protein function

Protein name :

TNFRSF1A

Binds TNFα, mediates inflammation, apoptosis, and cell survival

Expected phenotype

Impaired inflammatory response, apoptosis defects

Human disease relevance

Mutations linked to TRAPS (auto-inflammatory syndrome)

Model applications

Inflammatory and apoptotic signaling models

Keywords:

TNF receptor, Apoptosis, Autoimmunity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Tnfrsf1a

conditional Knockout mouse

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