Target

Gene symbol :  
Tnip1
NCBI gene ID :  
57783
Gene full name :  
TNFAIP3-interacting protein 1
Synonym :  
ABIN-1

Protein function

Protein name :  
TNIP1
Inhibitor of NF-κB signaling; modulates inflammation and apoptosis

Expected phenotype

Hyperinflammation, autoimmune-like phenotype

Human disease relevance

Associated with lupus, psoriasis, and other autoimmune conditions

Model applications

Immunology and inflammation models

Keywords:

NF‑κB inhibitor, Apoptosis, Autoimmunity

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Tnip1

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe