Tpm1 conditional Knockout mouse

Target

Gene symbol :

Tpm1

NCBI gene ID :

22003

Gene full name :

Tropomyosin 1 alpha

Synonym :

TPM, TPM1γ, α-Tropomyosin

Protein function

Protein name :

TPM1

Stabilizes actin filaments in muscle and non-muscle cells

Expected phenotype

Heart defects, abnormal muscle structure

Human disease relevance

Associated with familial hypertrophic cardiomyopathy

Model applications

Muscle contraction, cardiac disease models

Keywords:

Actin binding, Muscle, Cardiomyopathy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Tpm1

conditional Knockout mouse

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