Trafd1 conditional Knockout mouse

Target

Gene symbol :

Trafd1

NCBI gene ID :

231712

Gene full name :

TRAF-type zinc finger domain containing 1

Synonym :

FLN29

Protein function

Protein name :

TRAF-type zinc finger domain-containing protein 1

Negative regulator of TLR and interferon signaling pathways

Expected phenotype

KO enhances response to pathogens and inflammation

Human disease relevance

Implicated in immune tolerance and autoimmunity

Model applications

Used in innate immunity and inflammatory response studies

Keywords:

TLR signaling, Inflammation, Immune modulation, Zinc finger

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Trafd1

conditional Knockout mouse

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