Target

Gene symbol :  
Trmt10a
NCBI gene ID :  
108943
Gene full name :  
TRNA methyltransferase 10A
Synonym :  
RG9MTD2

Protein function

Protein name :  
TRMT10A
Methyltransferase involved in tRNA modification (m¹G9 methylation)

Expected phenotype

Knockouts show impaired glucose homeostasis and brain development

Human disease relevance

Mutations cause microcephaly and early-onset diabetes

Model applications

Studied in tRNA biology, diabetes, and neurodevelopment

Keywords:

tRNA methylation, m¹G9, Diabetes, Neurodevelopment

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Trmt10a

conditional Knockout mouse

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Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

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Innovative technologies

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Easy access to models

Models with certified health status from professional breeders in US and Europe