Target

Gene symbol :  
Ttll1
NCBI gene ID :  
319953
Gene full name :  
Tubulin tyrosine ligase like 1
Synonym :  

Protein function

Protein name :  
Tubulin polyglutamylase TTLL1
Enzyme catalyzing tubulin polyglutamylation, regulating microtubule stability and ciliary function

Expected phenotype

Ciliary dysfunction and impaired microtubule modification

Human disease relevance

Ciliopathies

Model applications

Microtubule modification and cilia models

Keywords:

tubulin modification, cilium

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ttll1

conditional Knockout mouse

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