Target

Gene symbol :  
Txnip
NCBI gene ID :  
56338
Gene full name :  
Thioredoxin-interacting protein
Synonym :  
TBP-2, VDUP1

Protein function

Protein name :  
TXNIP
Binds thioredoxin; regulates redox state, metabolism, and inflammasome activation

Expected phenotype

Glucose intolerance, oxidative stress

Human disease relevance

Linked to diabetes, metabolic syndrome, and cardiovascular disease

Model applications

Metabolism and oxidative stress models

Keywords:

Redox, Metabolism, Inflammation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Txnip

conditional Knockout mouse

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