Target

Gene symbol :  
Ubap1
NCBI gene ID :  
67123
Gene full name :  
Ubiquitin-associated protein 1
Synonym :  
KIAA0162

Protein function

Protein name :  
UBAP1
ESCRT-I complex component, regulates ubiquitin-dependent endosomal sorting

Expected phenotype

Endosome sorting and trafficking defects

Human disease relevance

Mutations linked to hereditary spastic paraplegia

Model applications

Neurodegeneration, vesicle trafficking models

Keywords:

Ubiquitin, ESCRT, Neurology

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ubap1

conditional Knockout mouse

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