Uri1 conditional Knockout mouse

Target

Gene symbol :

Uri1

NCBI gene ID :

19777

Gene full name :

Unconventional prefoldin RPB5 interactor 1

Synonym :

URI1

Protein function

Protein name :

URI1

Transcriptional regulator and co-chaperone involved in Pol II assembly & stress response

Expected phenotype

Growth defects, increased UV sensitivity

Human disease relevance

Implicated in cancer and protein-folding diseases

Model applications

Transcription, stress-response, proteostasis

Keywords:

Pol II assembly, Co-chaperone, Stress

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Uri1

conditional Knockout mouse

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