Target

Gene symbol :  
Uros
NCBI gene ID :  
22276
Gene full name :  
Uroporphyrinogen III synthase
Synonym :  
Uros3

Protein function

Protein name :  
UROS
Catalyzes heme biosynthesis intermediate formation

Expected phenotype

Porphyria, photosensitivity

Human disease relevance

Cause of congenital porphyria

Model applications

Porphyrin metabolism and enzyme deficiency models

Keywords:

Heme biosynthesis, Porphyria

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Uros

conditional Knockout mouse

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