Target

Gene symbol :  
Usp12
NCBI gene ID :  
22217
Gene full name :  
Ubiquitin specific peptidase 12
Synonym :  
Ubh1, USP12L1

Protein function

Protein name :  
USP12
Deubiquitinase regulating protein stability and Notch/Wnt signaling

Expected phenotype

Altered signaling, proteostasis defects

Human disease relevance

Implicated in cancer, neurological conditions via signaling pathways

Model applications

Ubiquitin signaling and developmental models

Keywords:

DUB, Signaling, Proteostasis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Usp12

conditional Knockout mouse

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