Target

Gene symbol :  
Usp14
NCBI gene ID :  
59025
Gene full name :  
Ubiquitin-specific peptidase 14
Synonym :  
UBP6

Protein function

Protein name :  
USP14
Deubiquitinase at proteasome; controls degradation of ubiquitinated proteins

Expected phenotype

Neurodegeneration, ataxia-like phenotype

Human disease relevance

Linked to neurodegenerative disorders and protein homeostasis

Model applications

Proteasome function and neurodegeneration

Keywords:

DUB, Proteasome, Protein degradation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Usp14

conditional Knockout mouse

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