Target

Gene symbol :  
Usp3
NCBI gene ID :  
235441
Gene full name :  
Ubiquitin specific peptidase 3
Synonym :  

Protein function

Protein name :  
Ubiquitin carboxyl-terminal hydrolase 3
Deubiquitinating enzyme involved in DNA repair and chromatin remodeling

Expected phenotype

KO leads to increased DNA damage sensitivity

Human disease relevance

Implicated in genome stability and cancer

Model applications

Studied in ubiquitin signaling and DNA damage models

Keywords:

Deubiquitination, DNA repair, Chromatin, Ubiquitin protease

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Usp3

conditional Knockout mouse

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