Usp33 conditional Knockout mouse

Target

Gene symbol :

Usp33

NCBI gene ID :

170822

Gene full name :

Ubiquitin specific peptidase 33

Synonym :

VDU1

Protein function

Protein name :

Ubiquitin-specific protease 33

Deubiquitinating enzyme involved in centrosome function, cilia, and signaling

Expected phenotype

Knockouts show ciliary defects and impaired Sonic hedgehog signaling

Human disease relevance

Implicated in cancer progression and ciliopathies

Model applications

Used in studies of deubiquitination and cell signaling

Keywords:

Deubiquitinase, Centrosome, Cilia, SHH pathway

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Usp33

conditional Knockout mouse

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