Vps13a conditional Knockout mouse

Target

Gene symbol :

Vps13a

NCBI gene ID :

271564

Gene full name :

Vacuolar protein sorting 13 homolog A

Synonym :

Chac, chorein

Protein function

Protein name :

Vacuolar protein sorting-associated protein 13A

Involved in vesicle trafficking, lipid transport; large cytoplasmic protein

Expected phenotype

KO shows motor deficits and neurodegeneration

Human disease relevance

Mutations cause Chorea-Acanthocytosis (VPS13A disease)

Model applications

Model for neurodegeneration and lipid trafficking

Keywords:

VPS13A, Chorea-acanthocytosis, Vesicle trafficking, Neurobiology

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Vps13a

conditional Knockout mouse

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