Vps4a conditional Knockout mouse

Target

Gene symbol :

Vps4a

NCBI gene ID :

116733

Gene full name :

Vacuolar protein sorting 4A homolog

Synonym :

Vacuolar protein sorting 4A

Protein function

Protein name :

VPS4A

ATPase involved in endosomal sorting and membrane scission.

Expected phenotype

Embryonic lethality or severe developmental defects

Human disease relevance

Linked to ESCRT machinery function in viral budding

Model applications

Intracellular trafficking, development

Keywords:

ESCRT, Endosome, Membrane dynamics

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Vps4a

conditional Knockout mouse

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