Vsig4 conditional Knockout mouse

Target

Gene symbol :

Vsig4

NCBI gene ID :

278180

Gene full name :

V-set and immunoglobulin domain containing 4

Synonym :

Z39Ig, CRIg

Protein function

Protein name :

VSIG4

Complement receptor on macrophages; negatively regulates T-cell responses.

Expected phenotype

Enhanced T-cell activation, altered immune clearance

Human disease relevance

Target in autoimmunity, sepsis, and cancer immunity

Model applications

Complement regulation, macrophage function

Keywords:

CRIg, Complement, Immune checkpoint

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Vsig4

conditional Knockout mouse

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