Target

Gene symbol :  
Wdr45
NCBI gene ID :  
54636
Gene full name :  
WD repeat domain 45
Synonym :  
WIPI4

Protein function

Protein name :  
WDR45
Regulates autophagy via phosphoinositide binding and trafficking.

Expected phenotype

Neurodegeneration, motor defects

Human disease relevance

Causes BPAN (beta-propeller protein-associated neurodegeneration)

Model applications

Autophagy, neurodegeneration

Keywords:

WIPI family, Autophagy, BPAN

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Wdr45

conditional Knockout mouse

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