Wdr45 conditional Knockout mouse

Target

Gene symbol :

Wdr45

NCBI gene ID :

54636

Gene full name :

WD repeat domain 45

Synonym :

WIPI4

Protein function

Protein name :

WDR45

Regulates autophagy via phosphoinositide binding and trafficking.

Expected phenotype

Neurodegeneration, motor defects

Human disease relevance

Causes BPAN (beta-propeller protein-associated neurodegeneration)

Model applications

Autophagy, neurodegeneration

Keywords:

WIPI family, Autophagy, BPAN

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Wdr45

conditional Knockout mouse

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