Whrn conditional Knockout mouse

Target

Gene symbol :

Whrn

NCBI gene ID :

73750

Gene full name :

Whirlin

Synonym :

DFNB31

Protein function

Protein name :

Whirlin

Scaffolding protein involved in stereocilia and photoreceptor development

Expected phenotype

Knockouts cause hearing loss and retinal dysfunction

Human disease relevance

Mutations cause Usher syndrome type 2D and DFNB31 deafness

Model applications

Used in hearing loss and sensory neuron development research

Keywords:

Hearing, Retina, Usher syndrome, Stereocilia

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Whrn

conditional Knockout mouse

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