Wrap53 conditional Knockout mouse

Target

Gene symbol :

Wrap53

NCBI gene ID :

216853

Gene full name :

WD repeat containing, antisense to TP53

Synonym :

Tcab1

Protein function

Protein name :

WD repeat-containing protein WRAP53

Involved in telomere maintenance and Cajal body formation; regulates TP53 transcript

Expected phenotype

KO disrupts telomerase trafficking and RNA processing

Human disease relevance

Associated with dyskeratosis congenita, cancer

Model applications

Studied in telomerase function, RNA biology, and cancer

Keywords:

Telomerase, Cajal body, TP53 regulation, RNA processing

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Wrap53

conditional Knockout mouse

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