Target

Gene symbol :  
Wsb2
NCBI gene ID :  
59043
Gene full name :  
WD repeat and SOCS box-containing protein 2
Synonym :  
WSB2, NRF2-binding protein

Protein function

Protein name :  
WSB2
E3 ubiquitin ligase adaptor; modulates protein turnover and signaling

Expected phenotype

Growth delay, signaling dysregulation

Human disease relevance

Roles in cancer and cell signaling under investigation

Model applications

Ubiquitin signaling and developmental biology

Keywords:

SOCS box, Ubiquitination, Signaling

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Wsb2

conditional Knockout mouse

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