Target

Gene symbol :  
Xaf1
NCBI gene ID :  
327959
Gene full name :  
XIAP associated factor 1
Synonym :  
XIAPAF1

Protein function

Protein name :  
XAF1
Antagonizes XIAP and promotes apoptosis under stress conditions.

Expected phenotype

Altered apoptosis response

Human disease relevance

Tumor suppressor with prognostic relevance in cancer

Model applications

Apoptosis regulation, stress response

Keywords:

XIAP, Apoptosis, Tumor suppressor

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Xaf1

conditional Knockout mouse

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