Target

Gene symbol :  
Xiap
NCBI gene ID :  
11798
Gene full name :  
X-linked inhibitor of apoptosis
Synonym :  
MIHA, BIRC4

Protein function

Protein name :  
XIAP protein
Inhibits caspases and regulates apoptosis and immune signaling

Expected phenotype

Increased apoptosis and immune defects

Human disease relevance

Immunodeficiency, cancer

Model applications

Apoptosis and immune regulation models

Keywords:

apoptosis, caspase inhibition

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Xiap

conditional Knockout mouse

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