Zc3h12a conditional Knockout mouse

Target

Gene symbol :

Zc3h12a

NCBI gene ID :

230738

Gene full name :

Zinc finger CCCH-type containing 12A

Synonym :

Regnase-1, Mcpip1

Protein function

Protein name :

Regnase-1 RNase

Endoribonuclease regulating mRNA stability of inflammatory genes

Expected phenotype

Severe immune dysregulation and inflammation

Human disease relevance

Autoimmune disease, inflammation

Model applications

Immunology and RNA regulation models

Keywords:

RNA degradation, inflammation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Zc3h12a

conditional Knockout mouse

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