Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate abeta formation, induces behavioral deficits and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice.

February 11, 2011
J Biol Chem
https://pubmed.ncbi.nlm.nih.gov/21148560

This article is currently being updated. View its version on PubMed.

https://pubmed.ncbi.nlm.nih.gov/21148560

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