Enhance the translatability of the immune/efficacy-related effects of biologics using one humanized mouse model
October 20, 2026
Duration: 31 min
Content
▶️ genO-BRGSF-HIS mice recapitulate key CRS features induced by biologics tested in the clinic
▶️ Immune cells are recruited, polarized and activated in the tumor microenvironment in genO-BRGSF-HIS mice
▶️ genO-BRGSF-HIS enables the assessment of both efficacy and safety in a single model
Speaker

Fabiane Sônego, PhD in Immunology and Pharmacology, is the Director of Preclinical Models and Services at genOway. She has extensive expertise in in vivo models for immuno-oncology and inflammation and a proven track record of supporting researchers in advancing translational research and accelerating drug development.
Scientific excellence
From model design to experimental results
Featured in 600+ scientific articles
Collaborative approach
Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions
Robust validation data on catalog models
Generated with biopharma partners and in-house
Innovative technologies
and guaranteed freedom to operate
Easy access to models
Models with certified health status from professional breeders in US and Europe
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