Exploring tumor-immune interactions in genO‑BRGSF‑HIS mice: myeloid and lymphoid cell recruitment dynamics

November 20, 2025

Duration: 31 min

Content

▶️ genO-BRGSF-HIS mouse model develops both human lymphoid and myeloid compartments

▶️ TME in genO-BRGSF-HIS mice is shaped by tumor type and tumor burden

▶️ genO-BRGSF-HIS is suitable to investigate efficacy and Immune-Related Adverse Events of therapeutics

Speaker

Fabiane Sônego, PhD in Immunology and Pharmacology, is the Director of Preclinical Models and Services at genOway. She has extensive expertise in in vivo models for immuno-oncology and inflammation and a proven track record of supporting researchers in advancing translational research and accelerating drug development.

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Exploring tumor-immune interactions in genO‑BRGSF‑HIS mice: myeloid and lymphoid cell recruitment dynamics

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genO‑BRGSF‑HIS

genO‑BRGSF‑HIS mice possess the most functional reconstituted human immune system currently on the market and are highly relevant for translational research.

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