Exploring tumor-immune interactions in genO‑BRGSF‑HIS mice: myeloid and lymphoid cell recruitment dynamics
November 20, 2025
Duration: 31 min
Content
▶️Functional human myeloid and lymphoid cells, including γδ T cells and NK develop in genO-BRGSF-HIS
▶️Recruitment of these cells into the tumor microenvironment is observed to be tumor type- and burden-dependent
▶️The model represents a platform for assessing the efficacy and mechanism of action of immunotherapies
Speaker

Fabiane Sônego, PhD in Immunology and Pharmacology, is the Director of Preclinical Models and Services at genOway. She has extensive expertise in in vivo models for immuno-oncology and inflammation and a proven track record of supporting researchers in advancing translational research and accelerating drug development.
Scientific excellence
From model design to experimental results
Featured in 600+ scientific articles
Collaborative approach
Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions
Robust validation data on catalog models
Generated with biopharma partners and in-house
Innovative technologies
and guaranteed freedom to operate
Easy access to models
Models with certified health status from professional breeders in US and Europe

