Target

Gene symbol :  
Dll3
NCBI gene ID :  
13389
Gene full name :  
Delta-like canonical Notch ligand 3
Synonym :  
Delta-like 3

Protein function

Protein name :  
DLL3
Atypical Notch ligand; regulates somitogenesis during development.

Expected phenotype

Skeletal defects, disrupted segmentation

Human disease relevance

Associated with congenital scoliosis and cancer

Model applications

Developmental biology, neuroendocrine tumors

Keywords:

Notch signaling, Embryogenesis, SCLC

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Dll3

conditional Knockout mouse

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