Genetically Engineered Cell Lines
Our CRISPR/Cas9 gene-editing platform for customized cell line development is optimized for mammalian and human cells.
A major benefit for you and your research is our rigorous procedure to quickly assess the feasibility of using your own cell line, and adapt our process to your cell line's specifics, if need be. Genetic modifications designed and performed with our standards in your favorite cell line optimize the use of your existing data and avoid the need for new standardization experiments.
We ensure reliable and reproducible performance in murine or human:
- Breast cancer, colorectal cancer, diabetes, microglial, and hematopoietic cell lines
- Embryonic stem, induced pluripotent stem, neural stem cell, and more
Our cell line services
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Permanent inactivation of the target gene, and total absence of the protein
Point Mutation Knockins
Constitutively mutated nucleotides affecting the function of a given protein (gain/loss of function)
Insertion of fluorescent, bioluminescent proteins or biochemical tags
Controlled gene expression by targeting permissive loci such as Rosa26
Add a gene sequence of interest to an endogenous locus
Learn more about our cell line engineering service:
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