Applications of the genO‑hCCR8/hCCL1 mouse model

Useful applications for researchers working on different biomedical fields, such as immuno-oncology:

  • Assess the efficacy of CCR8 and/or CCL1-targeting therapeutics
    • Perform tumor growth inhibition assays in the context of monotherapies or combotherapies
  • Investigate the mode of action (MoA) of various compounds and understand their therapeutic potential

Features

  • Physiological regulation and expression pattern of human CCR8 and human CCL1
  • Functional CCR8/CCL1 signaling axis
  • Fully functional mouse immune system
  • Lack of expression of the murine target genes

Clients

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Model Delivery & Logistics

  • Breeding facilities in the US and Europe through our trusted partners:
  • Quick, compliant, and reliable door-to-door delivery worldwide
  • Models with certified SOPF health status from AAALAC-accredited and PHS-assured professional breeders in the US and Europe

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genO-hCCR8/hCCL1

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Preclinical Double-humanized genO-hCCR8/hCCL1 Mouse Model

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