genOway’s upcoming congresses – Come and meet us!

 

The genOway scientific and commercial team will be present at several conferences this year.

A good opportunity to meet us!

 

2023 EVENTS – Upcoming conferences confirmed where you can meet us


July 18–20 Tumor myeloid-directed therapies summit 2023, Boston, MA
   

 

Past events

KSNSWorkshop2023

May 26, 2023: 43rd Workshop of the Korean Society of Non-Clinical Study (KSNS), Suwon, KR

Precise and translational preclinical models for assessment of immune-targeting agents:

 Outlining BRGSF-HIS mice: immunodeficient mice displaying functional human lymphoid and myeloid compartments, without side effects

 Assessing efficacy and toxicity induced by immune checkpoint inhibitors, cell engagers and combo therapies in BRGSF-HIS mice, which displays a wide therapeutic window

 Showcase of assessment of immune targeting agents in syngeneic humanized models

StingSummit2023

May 9-11, 2023: STING & TLR-Targeting Therapies Summit, Boston, MA

Profiling STING and TLR-Targeted Therapies in Humanized Preclinical Models:

Focus on BRGS-HIS CD34+ reconstituted mice featuring human lymphoid and myeloid compartments and syngeneic humanized mouse models

 Characterization of the immune response in the mice

 Showcasing an assessment of STING and TR targeting agents in these models

CellEngager2023

April 25-27, 2023: 5th Annual Cell Engager Summit, Boston, MA

Challenging the predictability of preclinical models for assessment of cell engagers:

Focus on BRGSF-HIS hCD34+-reconstituted mice featuring human lymphoid and myeloid compartments and syngeneic humanized mouse models

 Characterization of the immune response in these mice

 Assessment of efficacy and irAE induced by cell engagers

FcRTTS2023

April 19–20, 2023: Fc Receptor Pathway Targeted Therapies, Boston, MA

How to enhance the transferability of Fc-targeted therapies in preclinical models? A question that Kader Thiam, Sr VP, Discovery - Preclinical Models & Services Kader Thiam answered brilliantly in his talk in Boston. He mentioned in particular:

 How recapitulating human Fc receptors expression pattern in mice

 How investigating biologics’ Fc modifications on effector function and pharmacokinetics in humanized models

 Innovative genOway mouse models expressing human Fc receptors, tools for translational evaluation of Fc receptor-targeted therapies

AACR 2023

April 14–19, 2023: AACR, Orlando, FL

The genOway Team was present at this event with a booth to discuss about our highly physiologically relevant humanized preclinical models and see how they can help accelerate scientific research project, from drug discovery, through preclinical studies, to IND filing. It also took part in the poster session with a poster about our BRGSF-HIS mouse model explaining how functional human myeloid cells in humanized BRGSF-HIS mice allow assessment of myeloid-directed therapies.

Immuno 2023 UK

March 28–29, 2023: Immuno Series UK, London

Kader Thiam, Sr VP, Discovery - Preclinical Models & Services, presented the talk: "Applicability and complementarity of syngeneic and BRGSF-HIS (Human Immune System) mouse models to assess efficacy and mechanism of action of mono- and combo-immunotherapies".

hPD-1

January 24–26, 2023: Tumor Models San Francisco 2023

genOway was present at this event with a booth. Kader Thiam presented a lecture titled “Precise and Translational Models for Assessment of Immune-Targeting Agents”:

Outlining BRGSF-HIS mice: immunodeficient mice displaying functional human lymphoid and myeloid compartments, without side effects

Assessing efficacy and toxicity induced by immune checkpoint inhibitors, cell engagers and combotherapies in BRGSF-HIS mice, which displays a wide therapeutic window

Showcase of assessment of immune targeting agents in immune checkpoint humanized models

 

Get the transcript

PDF-genoway_webinar_article_20230503

 

January 18, 2023: genOway's webinar on Immunotherapy & Preclinical Models

"Assessing efficacy and MoA of mono and combo immunotherapies in preclinical humanized models" (Organized by genOway with the support of BioInsights)

The development of innovative models allows for a more efficient evaluation of new cancer treatments and identification of predictive biomarkers of response right from the early phases of development of a therapeutic molecule until the late preclinical phases.

Discover through our one-hour webinar how our preclinical mouse models enable pharmaceutical industries and biotechs to validate the efficacy and nontoxicity of their antibodies in immunotherapies.

Kader Thiam (Senior Vice President, Discovery – Preclinical Models & Services, genOway) provided a broad view of our preclinical model pipeline.

Arjun Surya (Chief Executive Officer & Chief Scientific Officer, Curadev Pharma) discussed the assessment of their STING targeting agents in our humanized STING Knock-in mouse model.

Edward van der Horst (Senior Vice President, Sensei Biotherapeutics) discussed the conditionally active antibody SNS-101 and its inhibition of VISTA immune checkpoint activity in the acidic tumor microenvironment, leading to significant enhancement of antitumor effects in combination with anti-PD-1 antibodies in multiple syngeneic tumor models.

Through this webinar, you can learn more about:

  • The advantages of BRGSF-HIS models (with functional human lymphoid and myeloid compartments) to assess human targeted therapies, and investigate in particular the potential toxicity of compounds
  • The advantages of immunocompetent models which feature humanized immune checkpoints (in which the crosstalk between syngeneic tumor, immune and stroma cells is functional) for the investigation of the efficacy and mechanisms of action
  • The applicability and complementarity of syngeneic and BRGSF-HIS models to assess efficacy and MoA of immunotherapies
To get the replay of this webinar, or if you need more information on the choice of a preclinical model adapted to your research, please contact us.

 

This was 2022