Application of the genO-hICOS mouse model
Useful applications for researchers working on different biomedical fields, such as immuno-oncology, inflammation and autoimmunity:
- Assess the efficacy of hICOS-targeting therapeutics
- Investigate the mode of action (MoA) of hICOS-targeting compounds and understand their therapeutic potential
- Analyze the biodistribution of hICOS-targeting constructs
Features
- Physiological expression of human ICOS
- Functional T/B cell cooperation
- Fully functional mouse immune system
- Lack of expression of the murine target gene
Clients
