Preclinical humanized STING mouse model
Design of the hSTING mouse
The humanized STING model, developed by Knockin at the mouse STING locus, expresses a full human STING.
Different versions of hSTING models are available:
hSTING features
STING is entirely humanizedPhysiological regulation of the human STINGFully functional mouse immune systemLack of expression of the murine target gene, thus avoiding cross-reactivityhSTING validation*
Validation
STING agonist induces cytokine release in vivo
Cytokine levels were measured in serum from DMXAA- or GSK-compound-treated mice.
Discover related products to
hSTING
Preclinical humanized STING mouse model
Get in touch about
Let us know how we can help